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Cytokine storm: Acalabrutinib assists in calming down in COVID-19 patients in study

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The drug acalabrutinib, FDA-approved for the treatment of several types of B cell cancers, improved the oxygenation levels and decreased molecular markers of inflammation in a majority of 19 patients hospitalized...

Antibiotics: Recarbrio gets FDA approval for treatment of HABP/VABP

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Merck announced Friday that the U.S. Food and Drug Administration (FDA) has approved a supplemental New Drug Application (sNDA) for RECARBRIO™ (imipenem, cilastatin, and relebactam) for the treatment...

Brazil COVID-19 cases top 600K, US sends two million doses of hydroxychloroquine

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By NewsDesk  @infectiousdiseasenews Brazil’s Health ministry has reported an additional 60,000 COVID-19 cases since June 2,putting the country’s total case count at 614,000. In addition,...

Researchers urge halt in prescribing hydroxycholoroquine for COVID-19

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The sacred oath taken by physicians during graduation from medical school to “First do no harm,” the first words of the Hippocratic Oath, provides a strong impetus for a commentary just published...

Escherichia coli

Dual-mechanism antibiotic kills Gram-negative bacteria and avoids drug resistance

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Poison is lethal all on its own — as are arrows — but their combination is greater than the sum of their parts. A weapon that simultaneously attacks from within and without can take down even...

FDA approves Sirturo for treating children with pulmonary multidrug-resistant TB

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The Janssen Pharmaceutical Companies of Johnson & Johnson announced this week that the U.S. Food and Drug Administration (FDA) has granted approval for a new pediatric formulation of SIRTURO® (bedaquiline)....

Malaria: FDA approves artesunate for injection to treat severe forms

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By NewsDesk  @infectiousdiseasenews Frederick, Maryland company specializing in treatments for rare and neglected tropical diseases, Amivas, announced Tuesday that Artesunate for Injection 110 mg, powder...

First patient dosed in pivotal Phase 3 trial for novel antifungal for both treatment and prevention of serious fungal infections

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Cidara Therapeutics, Inc., a biotechnology company developing long-acting therapeutics to transform the standard of care for patients facing serious fungal or viral infections, and Mundipharma announced...

Anti-malaria drug, chloroquine, studied to determine ability to protect health workers from COVID-19

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With $9 million in philanthropic support, an international group of physicians and scientists is establishing a research network to evaluate promising therapies for COVID-19. The group, called the COVID-19...

Acinetobacter baumannii infections: Global Phase 3 ATTACK trial of Sulbactam-Durlobactam

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By NewsDesk  @infectiousdiseasenews Commercial stage biopharmaceutical company, Zai Lab Limited, announced today dosing of the first Chinese patient in the global ATTACK (Acinetobacter Treatment Trial...