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FDA issues an alert about some EpiPen auto-injectors

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FDA is alerting patients, caregivers and health care professionals that the labels attached to some EpiPen 0.3mg and EpiPen Jr 0.15mg auto-injectors, and the authorized generic versions, may block access...

3D print of influenza virus. The virus surface (yellow) is covered with proteins called hemagglutinin (blue) and neuraminidase (red). NIH

Flu drug, Xofluza, receives FDA approval

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The U.S. Food and Drug Administration (FDA) today approved Xofluza (baloxavir marboxil) for the treatment of acute uncomplicated influenza (flu) in patients 12 years of age and older who have been symptomatic...

High doses of acetaminophen, also known as Tylenol, can damage the liver. This figure shows how acetaminophen (APAP) is broken down into a reactive compound (NAPQI) that binds covalently to proteins at cysteine residues. While this effect is well known, it does not account for all of the changes observed in acetaminophen-induced liver failure. Researchers have reported that binding by the reactive compound NAPQI activates a protein modification pathway called glutathionylation, which impairs protein function. The research illuminates early steps in a cascade of failures that can cause tissue damage, liver failure and sometimes death by acetaminophen overdose. Image/ Chan et al., Molecular & Cellular Proteomics 2018

Acetaminophen: How it causes liver failure

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Acetaminophen is a common pain reliever found in every pharmacy. However, it is also the No. 1 cause of acute liver failure in the United States. In the liver, acetaminophen is converted into a new compound...

antibiotics Image/Brett_Hondow

Antibiotic overprescribing: Nearly half of outpatient prescriptions written without infection diagnosis

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Clinicians prescribed antibiotics without an infection-related diagnosis nearly half of the time and one in five prescriptions were provided without an in-person visit, according to research being presented...

Squamous cell carcinoma Image/National Cancer Institute

Skin cancer: FDA approves Libtayo, first treatment for cutaneous squamous cell carcinoma

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The U.S. Food and Drug Administration today approved Libtayo (cemiplimab-rwlc) injection for intravenous use for the treatment of patients with metastatic cutaneous squamous cell carcinoma (CSCC) or locally...

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Mycobacterium avium complex: New drug, Arikayce, receives FDA approval

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The U.S. Food and Drug Administration today approved a new drug, Arikayce (amikacin liposome inhalation suspension), for the treatment of lung disease caused by a group of bacteria, Mycobacterium avium...

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Hairy cell leukemia treatment, Lumoxiti, receives FDA nod

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The U.S. Food and Drug Administration this week approved Lumoxiti (moxetumomab pasudotox-tdfk) injection for intravenous use for the treatment of adult patients with relapsed or refractory hairy cell...

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GamaSTAN® immune globulin approved for hepatitis A and measles postexposure prophylaxis

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Grifols, a leading global producer of plasma-derived medicines, announced that the U.S. Food and Drug Administration (FDA) has approved a new formulation of its GamaSTAN® immune globulin (human) for...

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Proliferation of antibiotic resistant organisms is correlated with poor sanitation, unsafe water and higher incomes

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An international team of researchers from CDDEP, Australian National University and Cardiff University and the Monarch Institute has published a new study showing that the proliferation of disease-causing...

"We shouldn't limit ourselves to just single drugs or two-drug combinations in our medical toolbox," said Pamela Yeh (left), with Elif Tekin. Image/Reed Hutchinson/UCLA

Antibiotics: Grouping 4 or 5 existing medications could help slow antibiotic-resistant bacteria–UCLA researchers

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Scientists have traditionally believed that combining more than two drugs to fight harmful bacteria would yield diminishing returns. The prevailing theory is that that the incremental benefits of combining...