Volunteer for a Hookworm Infection Study at the George Washington Medical Faculty Associates

We are looking for healthy D.C.-area adults 18-45 years of age who are willing to participate in a research study on hookworm infection. This study will help us to understand hookworm disease, which affects over 700 million people in developing countries.

For additional information regarding this research study, please contact:

Clinical Trials at 202-994-8976 or [email protected]

Participants will receive $75 per visit as compensation for time and travel to GW Medical Faculty Associates.

This the “ad” displayed on the George Washington University MITM Clinical Research Group website.

Researchers are looking for volunteers to be infected with the blood-drinking nematode as part of a study to develop a hookworm vaccine and hopefully eradicate the neglected tropical disease that affects hundreds of million across the globe.

Necator americanus
Necator americanus (hookworm)

The current strategy for treating hookworm infections is to administer anti-worm drugs to children in endemic areas once per year. But this offers only a temporary fix, said David Diemert, an associate professor of microbiology, immunology and tropical medicine at George Washington.

“Since you don’t develop any immunity, kids just keep getting re-infected,” Dr. Diemert said. “And since many of these places are poor, rural areas, they don’t have the systems in place to make sure people are treated every year.”

There are concerns of the parasite developing resistance against the anti-helminths. A vaccine would prevent the infection and GW researchers are ready to go on to the next step.

In collaboration with the Sabin Vaccine Institute and with new funding from the National Institutes of Health, the GW researchers are testing two of their vaccine candidates on healthy, U.S. adults in the Washington, DC area to evaluate the effect of these vaccine candidates in preventing hookworm disease.

The challenge study will entail inoculating volunteers with the vaccine candidate and then infecting them with a dose of hookworm larvae to test its effectiveness in preventing the disease.

For more info, contact them HERE


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