According to new estimates published today, between 291,000 and 646,000 people worldwide die from seasonal influenza-related respiratory illnesses each year, higher than a previous estimate of 250,000 to 500,000 and based on a robust, multinational survey.
The new estimate, from a collaborative study by CDC and global health partners, appears this week in The Lancet. The estimate excludes deaths during pandemics.
“These findings remind us of the seriousness of flu and that flu prevention should really be a global priority,” says Joe Bresee, M.D., associate director for global health in CDC’s Influenza Division and a study co-author.
The new estimates use more recent data, taken from a larger and more diverse group of countries than previous estimates. Forty-seven countries contributed to this effort. Researchers calculated annual seasonal influenza-associated respiratory deaths for 33 of those countries (57 percent of the world’s population) that had death records and seasonal influenza surveillance information for a minimum of four years between 1999 and 2015. Statistical modeling with those results was used to generate an estimate of the number of flu-associated respiratory deaths for 185 countries across the world. Data from the other 14 countries were used to validate the estimates of seasonal influenza-associated respiratory death from the statistical models.
Poorest nations, older adults hit hardest by flu
Researchers calculated region-specific estimates and age-specific mortality estimates for people younger than 65 years, people 65-74 years, and people 75 years and older. The greatest flu mortality burden was seen in the world’s poorest regions and among older adults. People age 75 years and older and people living in sub-Saharan African countries experienced the highest rates of flu-associated respiratory deaths. Eastern Mediterranean and Southeast Asian countries had slightly lower but still high rates of flu-associated respiratory deaths.
Despite World Health Organization recommendations to use flu vaccination to help protect people in high-risk populations, few developing countries have seasonal flu vaccination programs or the capacity to produce and distribute seasonal or pandemic vaccines.
Global flu surveillance protects all nations, including U.S.
CDC works with global partners to improve worldwide capacity for influenza prevention and control. CDC has helped more than 60 countries build surveillance and laboratory capacity to rapidly detect and respond to influenza threats, including viruses with the potential to cause global pandemics. These efforts, along with technical support, has helped some partners generate estimates of influenza-associated deaths, which contributed to this global effort.
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Global surveillance also provides the foundation for selecting the viruses used to make seasonal flu vaccines each year. This helps improve the effectiveness of flu vaccines used in the United States. Global surveillance also is crucial to pandemic preparedness by identifying viruses overseas that might pose a human health risk to people in the United States.
“This work adds to a growing global understanding of the burden of influenza and populations at highest risk,” says CDC researcher Danielle Iuliano, lead author of The Lancet study. “It builds the evidence base for influenza vaccination programs in other countries.”
The study authors note that these new estimates are limited to flu-associated respiratory deaths and therefore may underestimate the true global impact of seasonal influenza. Influenza infection can create or exacerbate other health factors which are then listed as the cause of death on death certificates, for example cardiovascular disease, diabetes, or related complications. Additional research to estimate non-respiratory causes of flu-associated deaths are ongoing.
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With any influenza virus I can cope with play
I am a Muslim 5 times a day doing ablution in icy water, and my feet once a day but in warm water, do not work, calm, food and drink healthy.
And one more trump card. I have diabetes insipidus, another type of diabetes. With 4 years I take medicine adiuretin, 3 times a day. Now to me of 40 years For this illness I can drink 20 liters of water in day if to not accept a medicine. But even though I take the medicine, I still drink 3 to 5 liters of water a day. And as you know, the flu does not like water.
The increase in T-lymphocytes in the immunogram indicates the hyperactivity of the immune system. At a rate of 600 to 2500, I have 2835
Insufficient activity of T-suppressors leads to the predominance of the influence of T-helpers, which contributes to a stronger and more mundane response. At a rate of 450 to 850, I have 1808. T-killers, cytotoxic T-lymphocytes, CTL (a type of T-lymphocytes that carry out lysis of damaged cells of their own organism). Targets of T-killers are cells afflicted with intracellular parasites (which include viruses and certain types of bacteria), tumor cells. At a rate of 270 to 540 I have 945.
According to the immunologist, lymphocytosis as a result of elevated t-helpers.
My very strong immunity is the deputy head of the health department of the city of Almetyevsk and the immunologist of the city of Almetyevsk.
I did 2 immunogram analyzes. The immunogram will be presented if necessary
Based on my blood, you can create the most powerful medicine for influenza in the world
I can help in creating a medicine for influenza
Technology of production of medicines against influenza. Infect me first with the flu. When I get out, take my blood and allocate from there the blood component of immunoglobulin.
The immunoglobulin is copied.
The diagnosis of the nut was put illegally under pressure from Moscow. For inadequate letters, now can prove their adequacy 2 immunograms blood test.
So I hurry because I’m sick and I have to live for several years. The name of this disease I’ll tell in person. I will say that she is a rare internal incurable disease
I’m sick with the flu but in a very light form. I want to use my blood to create drugs against the flu
Please inform me upon receipt.
If necessary, I’ll send the address of the laboratory. I ask you to notify me on receipt
Seven states reported widespread influenza activity
This year, experts found nearly 10,000 confirmed cases of influenza.
This time last year, no state has reported widespread influenza activity with only 42 confirmed cases.
Mother received the flu from her
children – and was dead in two days
December 11, 2017
The CDC reports that about 750,000 people in the United States have contracted the flu.
The vaccine is effective at 10%
INFLUENZA VIRUS GROWS MORE THAN 600% IN COMPARISON WITH THIS PERIOD OF PAST YEAR
News | 14 December 2017, 7: 37
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