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Drug-resistant gonorrhea: Rapid and cheap assay can provide real-time surveillance

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By NewsDesk  @bactiman63 A dual therapy treatment regimen of expanded-spectrum cephalosporins (ESCs) plus azithromycin (AZM) is the recommended standard of care for gonorrhea. A strain of the Neisseria...

Yaws: Re-emergence followed a mass drug administration in Papua New Guinea

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Genome sequencing has shed light on the re-emergence of the bacterium that causes yaws, a neglected tropical disease of the skin, bones and joints. The re-emergence followed a mass drug administration...

COVID-19

Hydroxychloroquine and azithromycin to treat COVID-19 clinical trial begins

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A clinical trial has begun to evaluate whether the malaria drug hydroxychloroquine, given together with the antibiotic azithromycin, can prevent hospitalization and death from coronavirus disease 2019...

SARS-CoV-2

Hydroxychloroquine: Novartis reaches agreement with FDA to proceed with a Phase III clinical trial in hospitalized COVID-19 patients

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Novartis has reached an agreement with the US Food and Drug Administration (FDA) to proceed with a Phase III clinical trial with approximately 440 patients to evaluate the use of hydroxychloroquine for...

COVID-19 treatment: Potential harms of chloroquine, hydroxychloroquine and azithromycin

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Chloroquine, hydroxychloroquine and azithromycin are being used to treat and prevent COVID-19 despite weak evidence for effectiveness, and physicians and patients should be aware of the drugs’ potentially...

Zithromax FDA warning: Increased risk of cancer relapse with long-term use after Donor Stem Cell Transplant

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The Food and Drug Administration (FDA) issued a warning Friday concerning the long-term use of azithromycin (Zithromax, Zmax) for prophylaxis of bronchiolitis obliterans syndrome to patients who undergo...

Shigella infections treated with ciprofloxacin or azithromycin: CDC recommendations updated

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In a follow-up to recommendations published in April 2017, the Centers for Disease Control and Prevention (CDC) issued updated recommendations on management and reporting of Shigella infections that...

CDC warns that gonorrhea monotherapy could accelerate antibiotic resistance

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A recent CDC MMWR report shows that providers treated 81% of patients diagnosed with gonorrhea using CDC’s recommended dual therapy. While encouraging, nearly 1 in 5 patients were treated with a different...

Highly resistant gonorrhea case treated successfully with ertapenem

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In a follow-up on the first global report of HLAziR N. gonorrhoeae which is also resistant to ceftriaxone in a United Kingdom man, Public Health England (PHE) reports investigating a UK case of Neisseria...

Yaws: The first report of the emergence of azithromycin-resistant Treponema pallidum subsp. pertenue

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The Lancet has published a new study led by Oriol Mitjà, first author and researcher at the Barcelona Institute for Global Health (ISGlobal), a centre supported by the “la Caixa” Foundation,...