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Tuberculosis: Washington cases on the rise, officials on ‘heightened alert’

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NewsDesk @bactiman63 Washington state health officials are on heightened alert as cases of tuberculosis (TB) are on the rise. TB reporting decreased in 2020 during the first year of the pandemic. Though...

TB bacterium: UAB researcher describe how the exotoxin is secreted and trafficked

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Six years ago, Michael Niederweis, Ph.D., described the first known toxin of the deadly pathogen Mycobacterium tuberculosis (Mtb), an exotoxin that had gone undetected for 132 years. Now Niederweis...

Robert Koch: Titan of Microbiology

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On today’s podcast, I had the honor of talking to E.B. Fred Professor of Natural Sciences Emeritus at UW–Madison and author of the book, Robert Koch–A Life in Medicine and Bacteriology, Thomas...

TB

Intravenous BCG immunization has proven higher efficacy than injection

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By Amanda Rachel Brunetti Tuberculosis, caused by infection with Mycobacterium tuberculosis, is the top infectious cause of death in the world. An estimated 1.5 million people died of tuberculosis (TB)...

TB: Researchers find compound that reverses isoniazid resistance

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About 1.5 million people died of tuberculosis (TB) in 2017, making it the most lethal infectious disease worldwide. A growing rise in drug-resistant TB is a major obstacle to successfully treating the...

How Leprosy and Tuberculosis Bacteria Hijack Immune Cells in Early Infection

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  Leprosy-causing bacteria alter the behavior of the body’s macrophages(link is external), leading these normally protective immune cells to initiate nerve damage during early infection, a new...

TB

University of Sydney findings are the starting point for a new TB drug

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Antibacterial compounds found in soil could spell the beginnings of a new treatment for tuberculosis, new research led by the University of Sydney has found. Believed by many to be a relic of past centuries,...

Tuberculosis virulence factor identified, may be target for new drug

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Scientists have discovered the mechanism that hijacks the immune system’s response to tuberculosis, revealing an important new drug target for the disease that kills more than 1 million people each...

New Tufts study identifies differences between subpopulations of mycobacteria with variable antibiotic susceptibilities

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Tuberculosis is one of the most common infectious diseases in the world, infecting almost 10 million people each year. Treating the disease can be challenging and requires a combination of multiple antibiotics...

Aerosolized TB vaccine induces immune response in monkeys

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Researchers funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, have developed an investigational aerosol tuberculosis (TB) vaccine that...