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A Biosecurity Research Institute study has found important results in the fight against Zika virus: Culex mosquitoes do not appear to transmit Zika virus.

Researchers at Kansas State University’s Biosecurity Research Institute studied Culex species mosquitoes from across the country, including Vero Beach in Florida, which is near Miami-Dade County where mosquitoes are spreading Zika virus.



The research, “Culex species mosquitoes and Zika virus,” appears in the journal Vector-Borne and Zoonotic Diseases and involves researchers from Rutgers University, the University of Florida and the U.S. Department of Agriculture.

The findings are important for controlling Zika virus in Florida and preventing its spread to other parts of the country, said Dana Vanlandingham, lead author and assistant professor of virology in the College of Veterinary Medicine.

“It’s very important to know that Culex mosquitoes are not able to transmit Zika,” Vanlandingham said. “It enables people to target their control strategies so that they aren’t wasting time and effort on a mosquito that isn’t transmitting Zika virus.”

It is the first Zika virus research publication from the Biosecurity Research Institute. Before this study, Culex mosquitoes’ role in Zika virus was unclear. By studying Culex mosquitoes over a period of time, the researchers found that Zika virus did not multiply and instead disappeared in the species.

“This is great news,” said Stephen Higgs, co-author and director of the Biosecurity Research Institute. “We can check this particular group of mosquitoes off the list here in the U.S. and focus efforts of control on the mosquitoes that we know can infect, like Aedes aegypti and Aedes albopictus.”

The Centers for Disease Control and Prevention has identified Aedes aegypti, or yellow fever mosquito, and Aedes albopictus, or Asian tiger mosquito, as two species that transmit Zika virus. Both mosquitoes are widely distributed in the U.S. and are present in Kansas.

Culex mosquitoes are brown mosquitoes, while Aedes aegypti are black and Aedes albopictus are black and white. Culex mosquitoes transmit West Nile virus and Japanese encephalitis and live outside. Aedes aegypti and Aedes albopictus can live in and around houses in plant trays, spare containers or gutters.

“We need to know which mosquitoes to target and which mosquitoes not to target because mosquitoes live in different environments,” said Vanlandingham, whose research focuses on zoonotic viruses — such as Japanese encephalitis and chikungunya. “Some mosquitoes are found outside and some are more in people’s homes. You need to know this in order to target your efforts.”

Both Vanlandingham and Higgs emphasize the importance of personal responsibility in stopping the spread of Zika virus. Homeowners can get rid of small pools of water where mosquitoes breed and should use mosquito repellent as personal protection.

While a startup fund from the university’s College of Veterinary Medicine provided funding for this Biosecurity Research Institute study, there is still a need for additional national funding to support research that stops Zika virus, said Higgs, who also has studied chikungunya, a mosquito-borne virus that has a similar transmission cycle to that of Zika virus.

“We thought that this research is so important with what is going on that we were able to use startup funding,” Higgs said. “This research is basic research because we don’t know some of the most fundamental information about mosquitoes. Applied research — such as vaccines and diagnostics — are obviously very important, but there is a need for funding basic research as well.”


  1. […] Zika virus not transmitted by Culex mosquitoes: K-State researchers […]

  2. Adam Neira says:

    See this recent paper by Chinese researchers that gives an opposite finding to the one by Stephen Higgs, Dana L. Vanlandingham et al.



    “Zika virus replication in the mosquito Culex quinquefasciatus in Brazil”


    See what Fiocruz Medical Entomologist Dr. Ayres said about Culex Q. on this report from Sunday 25/7/2016



    “Culex Q. is a vector for Zika+. Joins the club with Aegypti & Albopictus !”


    (Don’t rely on Google Translate. Get a fluent Portuguese speaker to check all Brazilian media, like I’ve done since 2014. You need to have contacts on the ground in Brazil to know what is really going on. I do !)

    Thus the question of whether or not various subgenera of Culex are capable vectors for the Zika+ virus is still open. A good judge needs to consider all the available evidence and not cherry pick various studies.

    P.S. Does WHO’s 18/8 AFRICA report suggest a fourth vector for Zika+ has been found?

    Aedes luteocephalus


  3. […] Related: Zika virus not transmitted by Culex mosquitoes: K-State researchers […]

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