Chagas disease is a potentially life-threatening parasitic disease that affects  up to 300,000 people in the United States and millions in South America.

The current treatment regimen is–oral benznidazole in smaller twice-daily doses over 2 months

My guest today and his colleagues say high weekly doses of oral benznidazole over 30 weeks resulted in better clearance of the parasite.

This research is outlined in a recent study published in the journal Science Translational Medicine.

Joining me today is Regents’ Professor in the University of Georgia’s department of cellular biology, Rick Tarleton, PhD

Show notes:  A modified drug regimen clears active and dormant trypanosomes in mouse models of Chagas disease


Chagas disease: 1st local transmission in Missouri

Chagas disease, kissing bugs and the OSU survey

Neglected Tropical Diseases: Chagas disease and schistosomiasis

Chagas disease treatment, Lampit, receives FDA approval for use in children

Texas reports increase in kissing bugs, Could increase Chagas risk

World Chagas Disease Day: Raising awareness about the ‘silent and silenced disease’


Chagas in Black and White