In a follow-up on the first global report of HLAziR N. gonorrhoeae which is also resistant to ceftriaxone in a United Kingdom man, Public Health England (PHE) reports investigating a UK case of Neisseria gonorrhoeae acquired in South East Asia which had high-level resistance to the 2 antibiotics, azithromycin and ceftriaxone, which are currently recommended for first-line treatment.


The case has now been successfully treated with another antibiotic, ertapenem.

Dr Gwenda Hughes, Consultant Scientist and Head of Sexually Transmitted Infection (STI) Section at PHE, said:

We are pleased to report that the case of multi-drug resistant gonorrhoea has been successfully treated. Investigations have also revealed there has been no further spread of this infection within the UK. PHE continues to actively monitor and tackle the spread of antibiotic resistance in gonorrhoea and potential treatment failures.

Two similar cases have just been reported in Australia and serve as a timely reminder that we expect to see further cases of multi-drug resistant gonorrhoea in the future. These cases will be challenging for healthcare professionals to manage. We urge the public to avoid getting or passing on gonorrhoea by using condoms consistently and correctly with all new and casual partners. If you think you have been at risk, you should seek an STI screen at a sexual health clinic.


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