The Public Health Laboratory Services Branch (PHLSB) of the Centre for Health Protection (CHP) of the Department of Health confirmed today (June 10) a case of New Delhi metallo-β-lactamase-1 (NDM-1) Carbapenemase-producing Enterobacteriaceae affecting an 8-month-old baby girl.

Klebsiella pneumoniae/CDC
Klebsiella pneumoniae/CDC

The patient, with underlying illness, had been hospitalised in India after birth and came to Hong Kong in November 2013. She developed cough, shortness of breath and vomiting since May 26 and was admitted to a private hospital on June 1. She has been in stable condition all along and was discharged on June 4.

The patient’s urine sample yielded NDM-1 Carbapenemase-producing Enterobacteriaceae as confirmed by the PHLSB. Her home contacts are asymptomatic. The CHP’s investigations are ongoing.

This is the 47th detected case of NDM Carbapenemase-producing Enterobacteriaceae in Hong Kong. For more infectious disease news and information, visit and “like” the Infectious Disease News Facebook page

NDM is an enzyme which can inactivate carbapenems and other beta-lactams such as penicillins. Bacteria harbouring this NDM gene are commonly resistant to multiple antimicrobials, limiting therapeutic options and rendering severe clinical infections difficult to treat.

Most bacteria with the NDM enzyme remain susceptible to two types of antibiotics, colistin and tigecycline. Infections vary from being asymptomatic to potentially life-threatening or fatal. The level of risk depends on which part of the body is affected by the infection, and the general health of the patient.