By NewsDesk  @bactiman63

Three additional wild poliovirus type 1 (WPV1) cases have been reported in the past week in Pakistan (2) and Afghanistan (1), bringing the total to 29 in 2019, according to the Global Polio Eradication Initiative.

Afghanistan Pakistan map/Public domain image- Pahari Sahib

In Pakistan, both WPV1 cases were reported from Bannu district, Khyber Pakhtunkhwa province. Pakistan has seen 21 cases year-to-date.

In Afghanistan, a case was reported in Kunar province, bringing the total number of WPV1 cases for 2019 to eight.

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In addition, one new circulating vaccine-derived poliovirus type 2 (cVDPV2) case was reported in the past week, from Diffa province, Niger. It is the first cVDPV2 case from the country in 2019.

Lastly, The Lancet published the results this week of the first in-human, Phase 1 clinical trial for nOPV2 – a key first step toward determining the potential for a novel type-2 oral polio vaccine that would provide the same level of protection against type-2 poliovirus as OPV without the same risk of reverting into cVDPV2 in under-immunized populations. These initial results are promising, and suggest the vaccine is safe and immunogenic in adults; further clinical trial results will be important to evaluate nOPV as a potential tool to sustain a world free from all types of polioviruses.