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The National Institute for Communicable Diseases (NICD) reports rabies was diagnosed in a 37-year-old male from Ginyintsimbi Village, Mbhashe Municipality, Amathole District of the Eastern Cape province during June 2023.

It was reported that he was bitten on the lip by his own dog approximately three weeks prior to the onset of illness. The dog died about a week after the instance but it was reported that there was no attempt to
confirm the cause of death.
Reportedly, the man self-treated the wound at home and did not attempt to access medical advice and therefore also did not receive rabies post-exposure prophylaxis (PEP).
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The diagnosis was confirmed through testing of ante-mortem collected saliva samples and RT-PCR testing at the NICD.
Between 1 January 2023 until 20 June 2023, a total of six laboratory confirmed human rabies cases were reported in South Africa. These cases culminated from the Eastern Cape (n=3), KwaZulu-Natal (n=2), and Limpopo (n=1).
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