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Libya: More vaccines arrive in Tripoli

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The third UNICEF-chartered plane has arrived at Mitiga airport, Tripoli, completing the delivery of a total 4.7 million doses of Measles, Rubella and Polio vaccines, as well as 2.75 million doses of Vitamin...

3D print of influenza virus. The virus surface (yellow) is covered with proteins called hemagglutinin (blue) and neuraminidase (red). NIH

Rheumatoid arthritis: High-dose influenza vaccination improves immune responses against flu

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High-dose influenza vaccination substantially improves immune responses against influenza in adults with seropositive rheumatoid arthritis, according to new research findings presented this week at the...

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Chikungunya vaccine candidate progresses in Phase 1 study

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Valneva SE, a commercial stage biotech company focused on developing innovative lifesaving vaccines, today announced progress in its Phase 1 program targeting a single-shot vaccine against Chikungunya.  The...

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Battling biothreats: Dual anthrax-plague vaccine a strong candidate

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Childhood vaccines: IDSA statement on new CDC data

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In response to a recent report from the Centers for Disease Control and Prevention (CDC) on a small but growing population of children are not getting vaccinated, the Infectious Diseases Society of...

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Marburg vaccine: Walter Reed Army Institute of Research begins phase 1 clinical trial

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The Walter Reed Army Institute of Research (WRAIR) this week administered the first vaccine in a Phase 1 clinical trial to evaluate the safety and immunogenicity of a Marburg vaccine candidate in healthy...

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Topic: Vaccines at Oregon Governor’s debate

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During their final debate for the Oregon’s Governor’s seat last week, one of the topics addressed was vaccines. Democratic Incumbent Governor Kate Brown squared off with her Republican challenger,...

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Philippines Dengvaxia controversy results in dramatic drop in public vaccine confidence

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The Philippines’ highly politicized response to newly-reported risks of a dengue vaccine led to a dramatic drop in public trust in vaccines overall, according to new research published in Human...

Image/ C. S. Goldsmith, P. Rollin, M. Bowen This transmission electron micrograph (TEM) depicted numbers of Lassa virus virions adjacent to some cell debris. The virus, a member of the virus family Arenaviridae, is a single-stranded RNA virus, and is zoonotic, or animal-borne that can be transmitted to humans. The illness, which occurs in West Africa, was discovered in 1969 when two missionary nurses died in Nigeria, West Africa.In areas of Africa where the disease is endemic (that is, constantly present), Lassa fever is a significant cause of morbidity and mortality. While Lassa fever is mild or has no observable symptoms in about 80% of people infected with the virus, the remaining 20% have a severe multisystem disease. Lassa fever is also associated with occasional epidemics, during which the case-fatality rate can reach 50%. There are a number of ways in which the virus may be transmitted, or spread, to humans. The Mastomys rodents shed the virus in urine and droppings. Therefore, the virus can be transmitted through direct contact with these materials, through touching objects or eating food contaminated with these materials, or through cuts or sores. Because Mastomys rodents often live in and around homes and scavenge on human food remains or poorly stored food, transmission of this sort is common. Contact with the virus also may occur when a person inhales tiny particles in the air contaminated with rodent excretions. This is called aerosol or airborne transmission. Finally, because Mastomys rodents are sometimes consumed as a food source, infection may occur via direct contact when they are caught and prepared for food.

Lassa fever and rabies vaccine shows promise in animal testing

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A novel vaccine designed to protect people from both Lassa fever and rabies showed promise in preclinical testing, according to new research published in Nature Communications. The investigational vaccine,...

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Traveler’s diarrhea: Researchers develop 3-in-1 vaccine

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A first-ever vaccine designed to deliver a one-two-three punch against the main causes of traveller’s diarrhea worldwide may result from new research published by a University of Guelph chemist. Prof....