By NewsDesk @infectiousdiseasenews
Health officials in Tuscany, Italy are reporting (computer translated) an outbreak of the superbug bacterium, New Delhi metallo-β-lactamase-1 (NDM-1) Carbapenemase-producing Enterobacteriaceae in hospitals since November 2018.
According to public health officials, a significant diffusion was observed in the north-western area of Tuscany.
T-shirts, coffee mugs and other merchandise with a clean, computerized image of a Giardia intestinalis trophozoite. See more at Giardia in Black and White
In Tuscany, the NDM-producing bacteria have been identified in the blood of patients admitted with serious pathologies and confirmed by molecular tests. The spread of NDM bacteria has affected many hospitals: in most cases it was colonization, but there have also been cases of serious infections in already compromised patients. Between November 2018 and August 31, 2019 the NDM bacteria were isolated in the blood of 75 patients .
The cases were lethal in 40% of patients with sepsis, a percentage comparable to lethality for this condition caused by other bacteria resistant to carbapenem antibiotics.
NDM is an enzyme which can inactivate carbapenems and other beta-lactams such as penicillins. Bacteria harbouring this NDM gene are commonly resistant to multiple antimicrobials, limiting therapeutic options and rendering severe clinical infections difficult to treat.
Most bacteria with the NDM enzyme remain susceptible to two types of antibiotics, colistin and tigecycline. Infections vary from being asymptomatic to potentially life-threatening or fatal. The level of risk depends on which part of the body is affected by the infection, and the general health of the patient.
- Polio update: 5 additional wild poliovirus cases reported this past week
- Colorado reports 1st hepatitis A death in Denver resident
- Romania measles outbreak update: 2,600 cases in 2019
- Pennsylvania reports 2nd possible measles exposure in York County
- Poor Motor Skills Predict Long-Term Language Impairments For Children with Autism, Rutgers Study Finds
- Egypt: 1st mass drug administration for trachoma
- Colombia reports 169 dengue deaths in 2019
- Karachi sees 13th Naegleria fowleri death of 2019
- Massachusetts reports 8th human EEE case
- Florida dengue: 4th autochthonous case in Miami-Dade