Since May 18, 2022, 11 people with monkeypox have been identified in NYC. Most of the initial cases
were likely infected during travel to Europe. However, recent cases report no travel and no exposure to
a person who traveled, suggesting person-to-person transmission of the virus is occurring in NYC.
Additional cases are expected.
In NYC and elsewhere the majority of reported cases are among gay, bisexual, and other men having sex with men (MSM), though anyone who has been in close contact with someone who has monkeypox is at risk. The locations of some of the presenting lesions are the genital and perianal regions, suggesting transmission occurred during sexual contact.
Monkeypox typically presents with a febrile prodrome 5 to 13 days after exposure (range: 4 to 17 days), which often includes lymphadenopathy, malaise, headache, and myalgia, followed 1 to 4 days later by the onset of a characteristic deep-seated, vesicular or pustular skin rash with a centrifugal distribution. The lesions are well circumscribed and often umbilicate or become confluent, progressing over time to scabs. Some recent cases have begun atypically, with lesions in the genital and perianal region and without subjective fever or other prodromal symptoms. Coinfection with monkeypox and other infectious agents that can cause a rash (i.e., syphilis, herpes simplex) have been reported.
According to the CDC Friday, the total confirmed monkeypox/orthopoxvirus cases stand at 49 in 16 states and the District of Columbia.
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